In the News

LSU VET MED DEAN RECEIVES PRESTIGIOUS BLAINE AWARD

Education

PhD, Royal Veterinary College (London), 1998

BVetMed, Royal Veterinary College (London), 1993

BSc, King's College London, 1990

CASLAT, Imperial College London 

Certifications and Licenses

Diplomate, American College of Veterinary Internal Medicine

Diplomate, European College of Veterinary Internal Medicine-Companion Animals

Fellow, Royal College of Veterinary Surgeons (UK)

Fellow, Higher Education Academy (UK)

Member, Royal College of Veterinary Surgeons (UK)

Fellow, Royal Society for the Encouragement of Arts, Manufactures and Commerce (UK)

Fellow, The College of Physicians of Philadelphia

Research Interest

My research focuses on mechanisms of peripheral tolerance in health and disease, spanning the mouse, rat and dog as model species of both autoimmune disease and cancer. My work has interrogated the role of regulatory T cells and more recently myeloid-derived suppressor cells in this context.

Awards & Honors

Undergraduate awards (BSc and BVetMed): Leaper Science Prize (1987), Frank Drury Anatomy Prize (1989), Tompson First Prize (1992), Centenary First Prize (1992)

British Society for Immunology (BSI) Best Poster Prize (of >400 posters on display), Annual Congress, December 2-5, 2003, Harrogate: Monk, CR, Spachidou, M, Rovis, F, Lechler, RI and Garden, OA (2003) MRL/Mp CD4+CD25- T cells resist suppression by CD25+ Tregs in vitro: a defect of effector cells in lupus? Immunology 110 (S1): 81

ProImmune Ltd Poster Prize, BSI Annual Congress, December 2-5, 2003, Harrogate: Rovis, F, Lee, B, Lechler, RI and Garden, OA (2003) Murine CD4+CD25+ Tregs: towards the identification of molecular markers. Immunology 110 (S1): 119

Nature Immunology Poster Prize, The Third International Conference on Regulatory T Cells and Helper  T  Cell  Subsets  and  Clinical  Applications  in  Human  Diseases,  October  13-16, 2012, Shanghai, China: Pinheiro, D, Pinney, JW and Garden, OA. A phylogenetic examination of regulatory networks within the Animalia Kingdom.

The Kennel Club International Canine Health Award for research into canine health and diseases: May 2017

Publications

Courreges, CJF, Davenport, ECM, Bilanges, B, Rebollo-Gomez, E, Hukelmann, J, Schoenfelder, P, Edgar, JR, Sansom, D, Scudamore, C, Roychoudhuri, R, Garden, OA, Vanhaesebroeck, B and Okkenhaug, K (2024) Lack of phosphatidylinositol 3-kinase VPS34 in regulatory T cells leads to a fatal lymphoproliferative disorder without affecting their development. Frontiers in Immunology 15:1374621 doi:10.3389/fimmu.2024.1374621

Banse, HE, Stough Hunter, A, Althouse, G, Anderson, S, Boudreaux, B, Chaney, K, Garden, OA, Navarre, C, Roush, JK, Schleining, JA, Seneca, E, Shivley, J, Ward, J and Raczkoski, B (2024) Cross-sectional survey of rural and non-rural veterinarians indicates similarities in intent to stay or leave practice and differences in community attachment and satisfaction. Journal of the American Veterinary Medical Association doi.org/10.2460/javma.24.08.0513

LeVine, DN, Goggs, R, Kohn, B, Mackin, AJ, Kidd, L, Garden, OA, Brooks, MB, Eldermire, ERB, Abrams-Ogg, A, Appleman, EH, Archer, TM, Bianco, D, Blois, SL,  Brainard, BM, Callan, MB, Fellman, CL, Haines, JM, Hale, AS, Huang, AA, Lucy, JM, O’Marra, SK, Rozanski, EA, Thomason, JM, Walton, JE and Wilson, HE (2024) ACVIM consensus statement of the treatment of immune thrombocytopenia in dogs and cats . Journal of Veterinary Internal Medicine 38(4): 1982-2007; doi:10.1111/jvim.17079

LeVine, DN*#, Kidd, L*#, Garden, OA*#, Brooks, MB*, Goggs, R*, Kohn, B, Mackin, AJ, Eldermire, ERB, Chang, Y-M, Allen, J, Christopherson, PW, Glanemann, B, Maruyama, H, Naskou, MC, Nielsen, LN, Shropshire, S, Viall, AK, Birkenheuer, AJ, Forman, MA, Hanzlicek, AS, Langner, KF., Lashnits, E, Lunn, KF, Makielski, KM, Roura, X and Spada, E (2024) ACVIM consensus statement on the diagnosis of immune thrombocytopenia in dogs and cats. Journal of Veterinary Internal Medicine 38(4): 1958-1981; doi: 10.1111/jvim.16996 [* Joint first authorship; # joint corresponding authorship]

Liu, P-Y, Xia, D, McGonigle, K, Carroll, AB, Chiango, J, Scavello, H, Martins, R, Mehta, S, Krespan, E, Lunde, E, LeVine, D, Fellman, CL, Goggs, R, Beiting, DP* and Garden, OA* (2023) Immune-mediated hematological disease in dogs is associated with alterations of the fecal microbiota: a pilot study. Animal Microbiome 5:46; doi 10.1186/s42523-023-00268-2 [*Dual last authorship]

Seligman, C, Chang, YM, Luo, J* and Garden, OA* (2023) Exploring the role of immune checkpoint inhibitors in the etiology of myasthenia gravis and Lambert-Eaton myasthenic syndrome: A systematic review. Frontiers in Neurology 13: 1004810; doi 10.3389/fneur.2022.1004810 [*Dual last authorship]

Ripolles-Garcia, A, Dolgova, N, Phillips, MJ, Savina, S. Ludwig, AL, Stuedemann, SA, Nlebedum, U, Wolfe, JH, Garden, OA, Gamm, DM, Aguirre, GD and Beltran, WA (2022) Systemic immunosuppression promotes survival and integration of subretinally-implanted hESC-derived photoreceptor precursor cells in dogs. Stem Cell Reports 17(8): 1824-1841; doi 10.1016/j.stemcr.2022.06.009

Glanemann, B, Seo, YJ, Priestnall, SL, Garden, OA, Kilburn, L, Rossoni-Serao, M, Segarra, S, Mochel, JP and Allenspach, K (2021) Clinical efficacy of prebiotics and glycosaminoglycans versus placebo in dogs with food responsive enteropathy receiving a hydrolyzed diet: A pilot study. PLOS ONE 16(10): e0250681; doi 10.1371/journal.pone.0250681

Forgash, JT, Chang, YM, Mittelman, NS, Petesch, S, Benedicenti, L, Galban, E, Hammond, JJ, Glass, EN, Barker, JR, Shelton, GD, Luo, J and Garden, OA (2021) Clinical features and outcome of acquired myasthenia gravis in 94 dogs. Journal of Veterinary Internal Medicine 35(5): 2315-2326; doi 10.1111/jvim.16223

Leopardi, V, Chang, YM, Pham, A, Luo, J and Garden, OA (2021) A systematic review of the potential implication of infectious agents in myasthenia gravis. Frontiers in Neurology 12: 618021; doi 10.3389/fneur.2021.618021

All Publications on PubMed